First-line endocrine therapy combined with CDK 4/6 inhibitor in disseminated carcinomatosis of bone marrow (DCBM) luminal breast cancer: a case report

Article / By

This case report discusses a 36-year-old premenopausal woman with advanced luminal breast cancer and disseminated carcinomatosis of bone marrow (DCBM), treated with a combination of endocrine therapy and a CDK4/6 inhibitor. The treatment led to significant symptom relief and improved quality of life, highlighting a novel approach for managing DCBM in luminal breast cancer patients.

First-line endocrine therapy combined with CDK 4/6 inhibitor in disseminated carcinomatosis of bone marrow (DCBM) luminal breast cancer: a case report Read More »

Clinical Impact of Somatic Genomic Testing on Breast Cancer Care

Article / By

The research discusses the clinical impact of somatic genomic testing on breast cancer care, highlighting its role in guiding adjuvant chemotherapy decisions for early-stage patients and identifying advanced disease patients who may benefit from targeted therapies. It reviews available tests within the NHS, their biological basis, and their clinical utility, while also addressing challenges in tissue-based testing and the potential of circulating tumor DNA testing.

Clinical Impact of Somatic Genomic Testing on Breast Cancer Care Read More »

SABCS 2024 Video Highlights

By

San Antonio Breast Cancer Symposium 2024 Conference coverage Video highlights from the San Antonio Breast Cancer Symposium (SABCS) 2024, taking place in San Antonio, TX from December 10 to 13, 2024. These clips will provide invaluable insights and updates on Breast Cancer research from SABCS 2024. Sorry, we couldn’t find any posts. Please try a

SABCS 2024 Video Highlights Read More »

Faculty 2024

By

Faculty – Breast Cancer Meet our Editorial Panel who are the key opinion leaders in the field of Breast Cancer. This expert panel in collaboration with the WILEY editorial team has curated the independent educational modules where you can get resources on the latest advancements in the diagnosis, treatment and management of Breast Cancer.  Javier

Faculty 2024 Read More »

Optimized biomarker evaluation and molecular testing in the era of breast cancer precision medicine

Article / By

The research discusses the evolution of precision medicine in breast cancer care, emphasizing the importance of advanced tumor testing and personalized treatment options. It highlights the need for standardization in pre-analytic factors to ensure high-quality tissue specimens for biomarker and molecular testing, which is crucial for effective patient care.

Optimized biomarker evaluation and molecular testing in the era of breast cancer precision medicine Read More »

Implementing geriatric assessment for dose optimization of CDK4/6 inhibitors in older breast cancer patients

Article / By

The research aims to investigate whether a lower starting dose of CDK4/6 inhibitors combined with endocrine therapy is as effective as the full dose in older patients (≥70 years) with advanced HR+/HER2- breast cancer who are assessed as vulnerable or frail. This study addresses the higher risk of adverse events associated with CDK4/6 inhibitors in older patients, as current practices often initiate treatment at lower doses without supporting evidence.

Implementing geriatric assessment for dose optimization of CDK4/6 inhibitors in older breast cancer patients Read More »

Training health workers in clinical breast examination for early detection of breast cancer in low‐ and middle‐income countries

Article / By

Most women living in low- and middle-income countries (LMICs) present with advanced-stage breast cancer. Limitations of poor serviceable health systems, restricted access to treatment facilities, and lack of breast cancer screening programmes all likely contribute to the late presentation of women with breast cancer living in these countries. Women are diagnosed with advanced disease and frequently do not complete their care due to a number of factors, including financial reasons as health expenditure is largely out of pocket resulting in financial toxicity; health system failures, such as missing services or health worker lack of awareness on common signs and symptoms of cancer; and sociocultural barriers, such as stigma and use of alternative therapies. Clinical breast examination (CBE) is an inexpensive early detection technique for breast cancer in women with palpable breast masses.

Training health workers in clinical breast examination for early detection of breast cancer in low‐ and middle‐income countries Read More »

Infographics

By

Infographics – Breast Cancer These infographics provide the entire multidisciplinary team with the latest information on Breast Cancer. Latest Content [Italian] Personalized Medicine and Cyclin-Dependent Kinase 4/6 (CDK4/6) Inhibitors in Breast Cancer Treatment [French] Personalized Medicine and Cyclin-Dependent Kinase 4/6 (CDK4/6) Inhibitors in Breast Cancer Treatment [Spanish] Personalized Medicine and Cyclin-Dependent Kinase 4/6 (CDK4/6) Inhibitors

Infographics Read More »

Articles

By

Articles – Breast Cancer A specially curated list of peer-reviewed articles discussing the latest advancements in the diagnosis and treatment of patients living with Early Breast Cancer & Metastatic Breast Cancer. Filter by TopicAbemaciclibAdherenceAdiposityAdjuvant TherapyAdjuvant Treatmentadvanced-stage breast cancerAKT inhibitorsAlpelisibAnastrozolearchive 2023Aromatase inhibitorBioavailabilityBody compositionBody imageBone-targeted deliveryBreast CancerCancer-specific promotersCapivasertibCDK inhibitorsCDK4/6CDK4/6 Inhibitor ResistanceCDK4/6 inhibitorsCDK4/6 ToxicityCell cycle inhibitionChemotherapyChitosanClinical TrialsConferenceCRISPRCutaneous ToxicityCyclin-dependent

Articles Read More »

Start typing and press enter to search

This site is only for use by healthcare professionals.

By continuing to view this site you are confirming that you are a healthcare professional.

Confirm